THE Graft™ Granule
Small / 0.25-1.00mm
2.00g / 4.80cc
purgo the graft, regenerative solution, natural procine-derived bone mineral matrix
THE Graft™ is a natural porcine-derived bone mineral matrix specifically designed for bone regeneration.
THE Graft™ is manufactured through a proprietary manufacturing process that maintains its original structure
and removes all organic components from pig bones, so there is no risk of immunogenicity and similar to the
physical and chemical properties of the mineralized matrix of human bones.
Sterilized by gamma irradiation, THE Graft™ is supplied in convenient vials containing cancellous granules,
ensuring both safety and ease of clinical handling. THE Graft™ integrates seamlessly within the healing process,
being gradually resorbed and naturally replaced by newly formed bone.
THE Graft™ Biocompatibility
THE Graft™ is structurally similar to human bone. It has high possible level of porosity combined with a natural
interconnectivity.
Safe & Biocompatible
The combination of porcine origin with the high level of purity enables predictable bone growth without risking
an immunogenic reaction.
In an In-Vitro study THE Graft™ was shown to encourage cell adhesion to the same extent as the compared
DBBM (Deproteinized bovine bone matrix), and therefore offering optimal conditions for vital cell growth.
Porosity is an important factor in determining tissue-implant material integration. High porosity leads to a quicker
absorption of liquids and cells spreading. THE Graft™ provides the optimized bone architecture for cells adhesions
and tissue regeneration.
THE Graft™ Purity
Proprietary virus inactivation process technology.
Thanks to highly efficient manufacturing process, THE Graft™ is free from any organic components that might be
potential causes of infection or immune reaction. In addition the unique process helps preserve the physical
properties of THE Graft™ with its native osseous structure.
A large surface area is a key requirement for graft materials, and not only results in a larger surface region
available for osteoblast cells attachment but also facilitates the exchange of nutrients and waste products,
it allows greater amounts of blood, proteins, and growth factors to be absorbed onto the scaffold.
THE Graft has a high purity.
The analysis result minimal residual protein, soft tissue, and organic bone matrix, proves that THE Graft™ is
deproteinized enough for safe use.
Other than THE Graft™, such low values for organic residues are only found with bone graft material treated
at high temperatures which may cause the detriment of the natural bone structure.
THE Graft™ High Porosity
High porosity and early remodeling improve clinical performance
The high porosity of THE Graft™ means a quicker absorption of fluids (e.g; blood) in comparison with DBBM.
This not only facilitates the application of the material but also leads to early remodelling and improved clinical
performance.
High level of porosity was demonstrated with particle pore structure test, particle size distribution test and total
porosity tests.
§Macropores (diameter > 100μm), are necessary to form blood vessels and induce both bone growth and
reorganization around the graft material.
§Micropores (diameter <10 μm), are required for the penetration of body fluids, ion transportation, the
attachment of osteoblasts, and the precipitation of newly formed HA.
§Nanopores are characterized by dimension of less than 100 nanometers pores size between grains.
Nano-porosity increases bone graft permeability to the physiological fluids and cells adhesion.
THE Graft™ Specifications
Resources
No resources available for this product yet.
Videos
No videos available for this product yet.
CREOSHOP Delivery
Pickup Locations
New York, NY 10018
Fishkill, NY 12524